钙在脑血流调节和失调中的作用。

Monographs on atherosclerosis Pub Date : 1986-01-01
E Betz
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引用次数: 0

摘要

钙不仅通过影响血管SMC的收缩状态来影响脑动脉系统,还通过调节大分子的跨内皮转运来影响脑动脉系统。此外,在动脉粥样硬化形成过程中,它在SMC的迁移和增殖中起决定性作用。通过钙进入阻滞剂在体内和SMC和成纤维细胞培养中的应用,阐明了钙在脑血管系统病理生理反应中的意义。
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The role of calcium in the regulation and dysregulation of cerebral blood flow.

Calcium influences the cerebral artery system not only through its action on the contractile state of the vessels' SMC, but also acts in the regulation of transendothelial transports of macromolecules. Additionally it plays a decisive role in migration and proliferation of SMC during the formation of atheromas. By means of calcium entry blockers used in vivo and in cultures of SMC and fibroblasts the significance of calcium for pathophysiological reactions of the cerebrovascular system is elucidated.

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