伏他仑®作为手术切除下智齿后的止痛药

Per-Åke Henrikson , Holger Thilander, Lars Å. Wåhlander
{"title":"伏他仑®作为手术切除下智齿后的止痛药","authors":"Per-Åke Henrikson ,&nbsp;Holger Thilander,&nbsp;Lars Å. Wåhlander","doi":"10.1016/S0300-9785(85)80022-3","DOIUrl":null,"url":null,"abstract":"<div><p>In a controlled trial, before having a lower wisdom tooth surgically removed, 190 patients were blindly randomized to 2 parallel groups. One group received 100 mg Voltaren® (diclofenac-sodium) before surgery and then 50 mg 3 times a day for 5 days; the other group in Sweden widely used fixed combination tablets (acetylsalicylic acid 500 mg, caffeine 50 mg, aprobarbital 20 mg, codeine phosphate 10 mg) in the highest recommended dose, 2 tablets when needed at most 3 times a day. Twice a day the patients recorded pain and swelling on 100 mm visual analogue scales. Patients treated with Voltaren had significantly less pain and swelling (<em>p</em> &lt; 0.001). Furthermore, they had significantly, fewer days away from work (<em>p</em> &lt; 0.01). The study indicates that visual analogue scales may also be useful in assessment of swelling and that Voltaren in a fixed dosage offers a promising alternative against postoperative pain and swelling.</p></div>","PeriodicalId":14224,"journal":{"name":"International journal of oral surgery","volume":"14 4","pages":"Pages 333-338"},"PeriodicalIF":0.0000,"publicationDate":"1985-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0300-9785(85)80022-3","citationCount":"47","resultStr":"{\"title\":\"Voltaren® as an analgesic after surgical removal of a lower wisdom tooth\",\"authors\":\"Per-Åke Henrikson ,&nbsp;Holger Thilander,&nbsp;Lars Å. Wåhlander\",\"doi\":\"10.1016/S0300-9785(85)80022-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In a controlled trial, before having a lower wisdom tooth surgically removed, 190 patients were blindly randomized to 2 parallel groups. One group received 100 mg Voltaren® (diclofenac-sodium) before surgery and then 50 mg 3 times a day for 5 days; the other group in Sweden widely used fixed combination tablets (acetylsalicylic acid 500 mg, caffeine 50 mg, aprobarbital 20 mg, codeine phosphate 10 mg) in the highest recommended dose, 2 tablets when needed at most 3 times a day. Twice a day the patients recorded pain and swelling on 100 mm visual analogue scales. Patients treated with Voltaren had significantly less pain and swelling (<em>p</em> &lt; 0.001). Furthermore, they had significantly, fewer days away from work (<em>p</em> &lt; 0.01). The study indicates that visual analogue scales may also be useful in assessment of swelling and that Voltaren in a fixed dosage offers a promising alternative against postoperative pain and swelling.</p></div>\",\"PeriodicalId\":14224,\"journal\":{\"name\":\"International journal of oral surgery\",\"volume\":\"14 4\",\"pages\":\"Pages 333-338\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1985-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0300-9785(85)80022-3\",\"citationCount\":\"47\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of oral surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0300978585800223\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of oral surgery","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0300978585800223","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 47

摘要

在一项对照试验中,190名患者在手术摘除下智齿之前被随机分为两个平行组。一组患者术前给予伏他仑(双氯芬酸钠)100 mg,术后给予50 mg,每日3次,连用5天;另一组在瑞典广泛使用最高推荐剂量的固定联合片剂(乙酰水杨酸500毫克,咖啡因50毫克,阿巴比妥20毫克,磷酸可待因10毫克),需要时2片,每天最多3次。患者每天两次在100 mm视觉模拟量表上记录疼痛和肿胀。用伏他仑治疗的患者疼痛和肿胀明显减轻(p <0.001)。此外,他们休假的天数明显减少(p <0.01)。该研究表明,视觉模拟量表也可用于评估肿胀,而固定剂量的伏他仑为缓解术后疼痛和肿胀提供了一种有希望的替代方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Voltaren® as an analgesic after surgical removal of a lower wisdom tooth

In a controlled trial, before having a lower wisdom tooth surgically removed, 190 patients were blindly randomized to 2 parallel groups. One group received 100 mg Voltaren® (diclofenac-sodium) before surgery and then 50 mg 3 times a day for 5 days; the other group in Sweden widely used fixed combination tablets (acetylsalicylic acid 500 mg, caffeine 50 mg, aprobarbital 20 mg, codeine phosphate 10 mg) in the highest recommended dose, 2 tablets when needed at most 3 times a day. Twice a day the patients recorded pain and swelling on 100 mm visual analogue scales. Patients treated with Voltaren had significantly less pain and swelling (p < 0.001). Furthermore, they had significantly, fewer days away from work (p < 0.01). The study indicates that visual analogue scales may also be useful in assessment of swelling and that Voltaren in a fixed dosage offers a promising alternative against postoperative pain and swelling.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
A case of large cell neuroendocrine carcinoma of the tongue Application of microendosurgery for extensive radicular cysts A case of epidermoid cyst arising in the left side of the root of the tongue A case of posterior open bite after bilateral coronoidectomy and aponeurectomy of the masseter muscles Development of standards for stored autologous blood transfunction. Adaptation to orthognathic surgery.:Adaptation to orthognathic surgery
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1