伏他仑®作为手术切除下智齿后的止痛药

Per-Åke Henrikson , Holger Thilander, Lars Å. Wåhlander
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引用次数: 47

摘要

在一项对照试验中,190名患者在手术摘除下智齿之前被随机分为两个平行组。一组患者术前给予伏他仑(双氯芬酸钠)100 mg,术后给予50 mg,每日3次,连用5天;另一组在瑞典广泛使用最高推荐剂量的固定联合片剂(乙酰水杨酸500毫克,咖啡因50毫克,阿巴比妥20毫克,磷酸可待因10毫克),需要时2片,每天最多3次。患者每天两次在100 mm视觉模拟量表上记录疼痛和肿胀。用伏他仑治疗的患者疼痛和肿胀明显减轻(p <0.001)。此外,他们休假的天数明显减少(p <0.01)。该研究表明,视觉模拟量表也可用于评估肿胀,而固定剂量的伏他仑为缓解术后疼痛和肿胀提供了一种有希望的替代方法。
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Voltaren® as an analgesic after surgical removal of a lower wisdom tooth

In a controlled trial, before having a lower wisdom tooth surgically removed, 190 patients were blindly randomized to 2 parallel groups. One group received 100 mg Voltaren® (diclofenac-sodium) before surgery and then 50 mg 3 times a day for 5 days; the other group in Sweden widely used fixed combination tablets (acetylsalicylic acid 500 mg, caffeine 50 mg, aprobarbital 20 mg, codeine phosphate 10 mg) in the highest recommended dose, 2 tablets when needed at most 3 times a day. Twice a day the patients recorded pain and swelling on 100 mm visual analogue scales. Patients treated with Voltaren had significantly less pain and swelling (p < 0.001). Furthermore, they had significantly, fewer days away from work (p < 0.01). The study indicates that visual analogue scales may also be useful in assessment of swelling and that Voltaren in a fixed dosage offers a promising alternative against postoperative pain and swelling.

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