John W. Foreman , Pamela D. McNamara , Louise M. Pepe , Kristina Ginkinger , Stanton Segal
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Uptake of proline by brushborder vesicles isolated from human kidney cortex
Proline transport into renal brushborder membrane vesicles isolated from human kidney is mediated by two uptake systems. The high-affinity system is stimulated by a Na gradient and appears to be shared with glycine while the low-affinity system is not. Uptake curves of low concentrations of proline exhibit a Nagradient-dependent overshoot indicative of electrogenic transport. The proline transport systems observed in isolated human renal brushborder membrane vesicles appear to have characteristics similar to those in rat kidney membranes.
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