亚甲二氧苯化合物的色谱分析

Lawrence Fishbein, Hans L. Falk, Paul Kotin
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引用次数: 10

摘要

色谱分析在阐述多种亚甲二氧苯衍生物的代谢、降解和作用方式方面发挥了重要作用。薄层色谱和气相色谱在分离和鉴定同分异构体混合物以及阐述取代基对亚甲基二氧基部分对色谱行为的影响方面非常有效。毫无疑问,各种色谱技术将站在尝试进一步阐述亚甲基-二氧苯增效剂可能的二元作用的前沿60,122。
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Chromatography of methylenedioxyphenyl compounds

Chromatographic analysis has played an important role in the elaboration of metabolism, degradation and mode of action of a variety of methylenedioxyphenyl derivatives. Thin-layer and gas chromatography have been singularly effective in the separation and identification of isomeric mixtures as well as elaborating the influence of substituents on the basic methylenedioxy moiety to chromatographic behavior.

A variety of chromatographic techniques undoubtedly will be in the forefront of attempts to further elaborate the possible dichotomy of action of the methylene-dioxyphenyl synergists60,122.

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