一种具有过氧化物酶活性的急性淋巴细胞白血病细胞系NALL-1。

In Vitro Pub Date : 1984-11-01 DOI:10.1007/BF02619636

J Yourno, W A Samsonoff, A Willey, P Burkhart, F Lizzi, A Tartaglia

{"title":"一种具有过氧化物酶活性的急性淋巴细胞白血病细胞系NALL-1。","authors":"J Yourno, W A Samsonoff, A Willey, P Burkhart, F Lizzi, A Tartaglia","doi":"10.1007/BF02619636","DOIUrl":null,"url":null,"abstract":"All cells examined from the non-B, non-T acute lymphoblastic leukemia cell line, NALL-1, stained positive both for terminal deoxynucleotidyl transferase and for common ALL antigen. In addition, peroxidase activity was detected by light microscopy in 55 to 75% of cells and peroxidase-positive granules were detected ultrastructurally in greater than 80% of cells. Peroxidase activity in NALL-1 may result from derepression of peroxidase genes or clonal proliferation of a biphenotypic precursor cell.","PeriodicalId":13317,"journal":{"name":"In Vitro","volume":"20 11","pages":"884-8"},"PeriodicalIF":0.0000,"publicationDate":"1984-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02619636","citationCount":"0","resultStr":"{\"title\":\"NALL-1, an acute lymphoblastic leukemia cell line with peroxidase activity.\",\"authors\":\"J Yourno, W A Samsonoff, A Willey, P Burkhart, F Lizzi, A Tartaglia\",\"doi\":\"10.1007/BF02619636\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"All cells examined from the non-B, non-T acute lymphoblastic leukemia cell line, NALL-1, stained positive both for terminal deoxynucleotidyl transferase and for common ALL antigen. In addition, peroxidase activity was detected by light microscopy in 55 to 75% of cells and peroxidase-positive granules were detected ultrastructurally in greater than 80% of cells. Peroxidase activity in NALL-1 may result from derepression of peroxidase genes or clonal proliferation of a biphenotypic precursor cell.\",\"PeriodicalId\":13317,\"journal\":{\"name\":\"In Vitro\",\"volume\":\"20 11\",\"pages\":\"884-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1007/BF02619636\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"In Vitro\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/BF02619636\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"In Vitro","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF02619636","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

所有来自非b、非t急性淋巴细胞白血病细胞系NALL-1的细胞，末端脱氧核苷酸转移酶和常见All抗原均呈阳性。55% ~ 75%的细胞光镜检测到过氧化物酶活性，80%以上的细胞超微结构检测到过氧化物酶阳性颗粒。NALL-1的过氧化物酶活性可能是由过氧化物酶基因的抑制或双表型前体细胞的克隆增殖引起的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

NALL-1, an acute lymphoblastic leukemia cell line with peroxidase activity.

All cells examined from the non-B, non-T acute lymphoblastic leukemia cell line, NALL-1, stained positive both for terminal deoxynucleotidyl transferase and for common ALL antigen. In addition, peroxidase activity was detected by light microscopy in 55 to 75% of cells and peroxidase-positive granules were detected ultrastructurally in greater than 80% of cells. Peroxidase activity in NALL-1 may result from derepression of peroxidase genes or clonal proliferation of a biphenotypic precursor cell.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

In Vitro

自引率

0.00%

发文量