1978-1982年健康儿童水痘疫苗接种:免疫学和临床反应及保护作用。

Biken journal Pub Date : 1984-09-01
K Horiuchi
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引用次数: 0

摘要

在1978年至1982年间,共有915名无水痘史的正常儿童接种了水痘活疫苗(Oka株)。接种疫苗后的临床反应为发热和轻微皮疹,仅有10例患儿出现。在所有524名被检查的儿童中观察到血清学反应。在可以跟踪的854名儿童中,602名儿童与水痘患者有过接触,但其中只有10名儿童患了极轻微的水痘并出现皮疹。轻度带状疱疹发生在一名因肺炎支原体住院的儿童中。
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Chickenpox vaccination of healthy children: immunological and clinical responses and protective effect in 1978-1982.

A total of 915 normal children without a history of varicella were immunized with a live varicella vaccine (Oka strain) between 1978 and 1982. As clinical reaction after vaccination, fever and or a slight rash was observed in only 10 children. A serological response was observed in all 524 children examined. Of the 854 children who could be followed, 602 children had contact with varicella patients, but extremely mild varicella with a rash developed in only 10 of them. Mild zoster occurred in one child who was admitted to hospital with mycoplasma pneumonia.

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