肾综合征出血热(HFRS)病毒在大鼠肿瘤标本中的分离。

Biken journal Pub Date : 1983-12-01
K Yamanishi, J R Dantas, M Takahashi, T Yamanouchi, K Domae, J Kawamata, T Kurata
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引用次数: 0

摘要

一株肾综合征出血热(HFRS)病毒从一个有HFRS病例的医疗机构饲养的大鼠肿瘤标本的细胞培养物中分离出来。第二代检测到与HFRS患者血清免疫荧光反应阳性,第三代检测到含抗原细胞增多。该病毒被命名为B-1株,通过对患者血清进行免疫荧光试验确定为HFRS病毒。
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Isolation of hemorrhagic fever with renal syndrome (HFRS) virus from a tumor specimen in a rat.

A strain of hemorrhagic fever with renal syndrome (HFRS) virus was isolated in a cell culture from a tumor specimen in a rat kept in a medical institution in which there was a case of HFRS. Positive immunofluorescent reaction with sera from HFRS patients was recognized at the second passage and the number of cells containing antigen increased in the third passage. This virus, named B-1 strain, was identified as the HFRS virus by immunofluorescent tests with sera from patients.

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