{"title":"[鞘内辣椒素和P物质对大鼠伤害阈值的急性影响]。","authors":"B Dib","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We have compared the effects of a single intrathecal injection of capsaicin or substance P (SP) on the motor responses to radiant heat and electrical nociceptive stimulations in the Rat. With nociceptive electrical stimulation, an immediate hyperalgesia followed capsaicin injection in all Rats. On the other hand, some Rats displayed hyperalgesia after SP while others showed hypoalgesia. Both capsaicin and SP, induced hypoalgesia to radiant heat in 17 rats. In 5 rats no response was obtained.</p>","PeriodicalId":10622,"journal":{"name":"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie","volume":"296 20","pages":"969-74"},"PeriodicalIF":0.0000,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Acute effects of intrathecal capsaicin and substance P on nociceptive thresholds in rats].\",\"authors\":\"B Dib\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We have compared the effects of a single intrathecal injection of capsaicin or substance P (SP) on the motor responses to radiant heat and electrical nociceptive stimulations in the Rat. With nociceptive electrical stimulation, an immediate hyperalgesia followed capsaicin injection in all Rats. On the other hand, some Rats displayed hyperalgesia after SP while others showed hypoalgesia. Both capsaicin and SP, induced hypoalgesia to radiant heat in 17 rats. In 5 rats no response was obtained.</p>\",\"PeriodicalId\":10622,\"journal\":{\"name\":\"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie\",\"volume\":\"296 20\",\"pages\":\"969-74\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Acute effects of intrathecal capsaicin and substance P on nociceptive thresholds in rats].
We have compared the effects of a single intrathecal injection of capsaicin or substance P (SP) on the motor responses to radiant heat and electrical nociceptive stimulations in the Rat. With nociceptive electrical stimulation, an immediate hyperalgesia followed capsaicin injection in all Rats. On the other hand, some Rats displayed hyperalgesia after SP while others showed hypoalgesia. Both capsaicin and SP, induced hypoalgesia to radiant heat in 17 rats. In 5 rats no response was obtained.
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