Na+,K+- atp酶在营养不良大鼠脑发育中的作用。

O P Mishra, R Shankar
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引用次数: 7

摘要

研究了营养不良大鼠脑内Na+,K+- atp酶的变化。出生后6 ~ 17天营养不良的动物Na+,K+- atp酶活性明显低于营养良好的对照组。康复4周后,酶活性下降部分恢复。营养不良后脑内阳离子含量未见变化。Na+, k4 - atp酶活性的降低可能是由于胆固醇含量的降低,可能是发育过程中与营养不良或营养不足相关的功能变化的原因。
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Na+,K+-ATPase in developing rat brain during undernutrition.
Na+,K+-ATPase was studied in developing rat brain during undernutrition. The activity of Na+,K+-ATPase was significantly lower in animals that were undernourished from 6 to 17 days after birth than in well-nourished controls. The decreased activity of the enzyme was partially recovered after 4 weeks of rehabilitation. No change in the cation contents of brain following undernutrition was observed. The decrease in Na+,K4-ATPase activity was possibly due to the reduction in cholesterol contents and could be responsible for the observed functional changes associated with malnutrition or undernutrition during development.
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