细胞色素c:化学识别的范例。

M D Kamen
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引用次数: 1

摘要

细胞色素c包括亚群,它们根据线粒体和某些细菌形式的基本三维结构的明确变化呈现出各种氧化还原功能,特别是细胞色素c2。这些蛋白质表现出重叠的功能和分级的结构序列,提供了非常适合澄清识别机制的范例。本文将根据细胞色素c2与线粒体细胞色素c氧化酶交叉反应的动力学分析,讨论细胞色素c的性质和分布,并阐述其结构和功能的关系。
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The cytochromes c: paradigms for chemical recognition.

The cytochromes c include subgroups which present a variety of redox functions based on well-defined changes in the basic three-dimensional structure exemplified by the mitochondrial and certain bacterial forms, in particular cytochromes c2. These proteins exhibit overlapping functionality and a graded sequence of structures which provide paradigms well suited for clarification of recognition mechanisms. The character and distribution of cytochromes c will be discussed and approaches to relatedness of structure and function will be described, based on kinetic analyses of cross reactivities of cytochromes c2 with mitochondrial cytochrome c oxidase.

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