{"title":"巴特氏综合征中性粒细胞功能","authors":"N. Lapointe, J. Samson, S. O'Regan","doi":"10.1016/0161-4630(81)90127-0","DOIUrl":null,"url":null,"abstract":"<div><p>Bartter's syndrome is a state associated with hyperprostaglandinemia and high urinary excretion of prostaglandin derivatives. Because of numerous reports on prostaglandins acting as local modulators of the immune system, we have studied parameters of phagocytic function and of cellular and humural immunity in four patients with this disease.</p><p>An augmentation in chemotaxis was identified in Bartter's syndrome neutrophils. Despite some minor deviations in other parameters measured, no other gross derangement in immune function could be identified.</p></div>","PeriodicalId":76381,"journal":{"name":"Prostaglandins and medicine","volume":"6 6","pages":"Pages 647-655"},"PeriodicalIF":0.0000,"publicationDate":"1981-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0161-4630(81)90127-0","citationCount":"1","resultStr":"{\"title\":\"Neutrophil function in Bartter's syndrome\",\"authors\":\"N. Lapointe, J. Samson, S. O'Regan\",\"doi\":\"10.1016/0161-4630(81)90127-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Bartter's syndrome is a state associated with hyperprostaglandinemia and high urinary excretion of prostaglandin derivatives. Because of numerous reports on prostaglandins acting as local modulators of the immune system, we have studied parameters of phagocytic function and of cellular and humural immunity in four patients with this disease.</p><p>An augmentation in chemotaxis was identified in Bartter's syndrome neutrophils. Despite some minor deviations in other parameters measured, no other gross derangement in immune function could be identified.</p></div>\",\"PeriodicalId\":76381,\"journal\":{\"name\":\"Prostaglandins and medicine\",\"volume\":\"6 6\",\"pages\":\"Pages 647-655\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0161-4630(81)90127-0\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Prostaglandins and medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0161463081901270\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Prostaglandins and medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0161463081901270","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Bartter's syndrome is a state associated with hyperprostaglandinemia and high urinary excretion of prostaglandin derivatives. Because of numerous reports on prostaglandins acting as local modulators of the immune system, we have studied parameters of phagocytic function and of cellular and humural immunity in four patients with this disease.
An augmentation in chemotaxis was identified in Bartter's syndrome neutrophils. Despite some minor deviations in other parameters measured, no other gross derangement in immune function could be identified.
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