{"title":"氯贝特饲喂对大鼠肝脏线粒体胆碱脱氢酶活性的影响。","authors":"R Kramar, K Kremser, R Raab","doi":"10.1515/bchm2.1984.365.2.1207","DOIUrl":null,"url":null,"abstract":"<p><p>Male rats were fed a diet containing 0.75% clofibrate. After three weeks, the specific activity of choline dehydrogenase of a liver mitochondrial fraction was more then doubled. However, the activity of two other NAD-independent flavoenzymes of the inner mitochondrial membrane namely proline and succinate dehydrogenases were not altered significantly. Thus changes of the inner mitochondrial membrane induced by clofibrate seem to be restricted to some particular enzymes.</p>","PeriodicalId":13015,"journal":{"name":"Hoppe-Seyler's Zeitschrift fur physiologische Chemie","volume":"365 10","pages":"1207-10"},"PeriodicalIF":0.0000,"publicationDate":"1984-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/bchm2.1984.365.2.1207","citationCount":"6","resultStr":"{\"title\":\"Enhancement of choline dehydrogenase activity in rat liver mitochondria by clofibrate feeding.\",\"authors\":\"R Kramar, K Kremser, R Raab\",\"doi\":\"10.1515/bchm2.1984.365.2.1207\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Male rats were fed a diet containing 0.75% clofibrate. After three weeks, the specific activity of choline dehydrogenase of a liver mitochondrial fraction was more then doubled. However, the activity of two other NAD-independent flavoenzymes of the inner mitochondrial membrane namely proline and succinate dehydrogenases were not altered significantly. Thus changes of the inner mitochondrial membrane induced by clofibrate seem to be restricted to some particular enzymes.</p>\",\"PeriodicalId\":13015,\"journal\":{\"name\":\"Hoppe-Seyler's Zeitschrift fur physiologische Chemie\",\"volume\":\"365 10\",\"pages\":\"1207-10\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1515/bchm2.1984.365.2.1207\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hoppe-Seyler's Zeitschrift fur physiologische Chemie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/bchm2.1984.365.2.1207\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hoppe-Seyler's Zeitschrift fur physiologische Chemie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/bchm2.1984.365.2.1207","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Enhancement of choline dehydrogenase activity in rat liver mitochondria by clofibrate feeding.
Male rats were fed a diet containing 0.75% clofibrate. After three weeks, the specific activity of choline dehydrogenase of a liver mitochondrial fraction was more then doubled. However, the activity of two other NAD-independent flavoenzymes of the inner mitochondrial membrane namely proline and succinate dehydrogenases were not altered significantly. Thus changes of the inner mitochondrial membrane induced by clofibrate seem to be restricted to some particular enzymes.
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