实验性雄性大鼠自身变应性涎腺炎。

D H Dean, R N Hiramoto
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引用次数: 3

摘要

采用免疫荧光法对大鼠颌下腺诱导的自身过敏性病变进行了研究。山羊抗大鼠IgG偶联物直接染色为阴性。间接免疫荧光显示,对照组和实验组血清中抗唾液管抗体的发生率均较高。在个体大鼠中,没有发现血清抗唾液抗体的存在或不存在与唾液自身过敏性病变的存在或不存在之间的关系。我们的结论是,所证明的抗体在疾病的发病机制中不起作用。
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Experimental auto-allergic sialoadenitis in male rats.

Induced auto-allergic lesions in the submandibular glands of rats were studied by immunofluorescence. Direct staining with a goat anti-rat IgG conjugate was negative. Indirect immunofluorescence revealed a high incidence of anti-salivary-duct antibodies in sera from both control and experimental groups. In individual rats, no relationship was found between the presence or absence of serum anti-salivary antibodies and the presence or absence of salivary auto-allergic lesions. We conclude that the antibodies demonstrated do not play a role in the pathogenesis of the disease.

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