[霍乱毒素a亚基γ链合成序列(10-24)的生物学特性]。

A Dodin, P N Yuan, G Le Thuillier, O Siffert, P Allard
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引用次数: 0

摘要

胆毒素合成片段的生物活性在体内研究了γ链A亚基。该五肽(10-24)采用固相法合成,最后采用高效液相色谱法纯化。与B亚基相关,肽抑制商业胆毒素引起的组织水分流失。
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[Biological properties of a synthetic sequence (10-24) of the gamma chain from sub-unit A of cholera toxin].

The biological activity of a synthetic fragment of choleric toxin. gamma Chain A subunit, was studied in vivo. This pentadecapeptide (10-24) was synthesized by solid phase method and finally purified by HPLC. Associated with the B subunit, the peptide inhibits the tissue water loss induced by commercial choleric toxin.

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