精神病发生的风险与癫痫类型和癫痫发作的关系。

A Sengoku, K Yagi, M Seino, T Wada
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引用次数: 25

摘要

根据癫痫和癫痫发作的类型,对可能存在的精神病发生风险进行了检查。本研究包括两个方面的调查:1)对879例癫痫患者进行调查,调查不同类型癫痫患者的精神病发生率;结果表明,颞叶癫痫的发病率最高,相对高于其他(非颞叶)部分癫痫,但与全面性癫痫的发病率无显著差异。2)对96例颞叶癫痫患者进行比较研究,其中48例为精神病性患者,48例为非精神病性患者作为对照组。比较两组癫痫发作症状的差异。结果发现,精神病组与非精神病组相比,全身性强直-阵挛性惊厥和复合癫痫表现的发生率明显更高。结果似乎支持这样一个事实,即颞叶癫痫表现的普遍化机制与影响精神病的生理病理因素密切相关。
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Risks of occurrence of psychoses in relation to the types of epilepsies and epileptic seizures.

The possible existence of the risks of occurrence of psychoses was examined in relation to the types of epilepsies and epileptic seizures. This study consisted of two investigations: 1) A study of 879 epileptic patients was conducted in which the incidence of psychoses in the different types of epilepsies was surveyed; the result was that the incidence in temporal lobe epilepsy was the highest, being relatively higher than that of other (non-temporal lobe) partial epilepsies but not significantly different from that of generalized epilepsies. 2) A comparative study was carried out on 96 patients with temporal lobe epilepsy in which 48 were psychotic and another 48 were non-psychotic which served as a control group. The differences of seizure symptomatology between the two groups were compared. The results were that the psychotic group was found to exhibit at a significantly higher rate generalized tonic-clonic convulsion and compound seizure manifestations in comparison with the non-psychotic group. The results appear to support the fact that generalizing mechanisms of temporal lobe epileptic manifestations are closely related to a physiopathogenic factor influencing psychoses.

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