R P Easmann, D E Steflik, D H Pashley, R V McKinney, G M Whitford
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引用次数: 22
摘要
本文描述了0.1盐酸或0.1盐酸中1,10或50 mM NaF对胃的超微结构和地形变化。0.1 N HCl(对照)和1 mM NaF在0.1 N HCl标本中没有形态学差异。在0.1 N HCl中，10毫摩尔NaF可引起表面粘膜上皮细胞部分脱屑，而50毫米NaF可引起胃腺开口周围细胞(凹窝)的广泛损伤以及凹窝间细胞的损失。
Surface changes in rat gastric mucosa induced by sodium fluoride: a scanning electron microscopic study.
This paper describes the ultrastructural, topographical changes seen in rat gastric mucosa following application of 0.1 N HCl or 1, 10 or 50 mM NaF in 0.1 N HCl to the stomach. No morphological differences were noticed between the 0.1 N HCl (control) and 1 mM NaF in 0.1 N HCl specimens. Ten milliomolar NaF in 0.1 N HCl produced some desquamation of surface mucous epithelial cells while 50 mM NaF produced extensive damage to cells surrounding the gastric gland openings (foveolae) as well as interfoveolar cell loss.
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