四环素加氨苄西林和丙戊酸单剂治疗淋病的优点。

G L Ridgway, J D Oriel
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引用次数: 7

摘要

沙眼衣原体从12名最初产生衣原体并仅接受氨苄西林和丙烯酸酯(AMP)治疗的淋病患者中的11人身上重新分离出来,但从5名接受氨苄西林和丙烯酸酯后再接受四环素(AMPT)治疗的患者身上没有分离出来。这些结果与接受AMPT治疗的组中没有淋球菌性尿道炎(PGU)相关。在接受AMP治疗的25名女性中,有20名女性分离出或再次分离出沙眼原体,而在接受AMPT治疗的14名女性中,没有分离出沙眼原体。我们建议在常规单剂量治疗淋病的基础上增加一个疗程的四环素。
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Advantages of adding a course of tetracycline to single dose ampicillin and probenecid in the treatment of gonorrhoea.

Chlamydia trachomatis was reisolated from 11 of 12 men with gonorrhoea who had initially yielded chlamydiae and who had been treated with ampicillin and probenecid (AMP) only, but from none of five such men treated with ampicillin and probenecid followed by tetracycline (AMPT). These results correlated with the absence of postgonococcal urethritis (PGU) in the group treated with AMPT. C trachomatis was isolated or reisolated from 20 of 25 women after treatment with AMP, compared with none of 14 women treated with AMPT. We recommend the addition of a course of tetracycline to the routine single dose treatment for gonorrhoea in men and women.

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