放射性氙-113吸入和动态发射断层扫描的局部脑血流。

Progress in nuclear medicine Pub Date : 1981-01-01
N A Lassen, L Henriksen, O B Paulson
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引用次数: 0

摘要

描述了一种快速旋转的单光子层析成像仪,用于以ml/ 100g /min测量rCBF的自动和三维测量。该仪器具有高灵敏度,可以记录在吸入浓度为10 mCi/l的气体1分钟期间和之后从人脑中摄取和冲洗氙-133的情况。描述了用于计算rCBF的算法,并介绍了特别是在中风病例中的临床结果。由于避免了组织层的叠加,快速旋转层析成像仪比传统的静止检测器更适合于局灶性脑缺血的研究。
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Regional cerebral blood flow by radioxenon-113 inhalation and dynamic emission tomography.

A rapidly rotating single photon tomograph is described for atraumatic and three-dimensional measurements of rCBF in ml/100 g/min. The instrument has a high sensitivity permitting the recording of the uptake and washout of xenon-133 from the human brain during and after inhalation of the gas at a concentration of 10 mCi/l for 1 min. The algorithm used to calculate rCBF is described, and clinical results in particular in stroke cases are presented. The rapidly rotating tomograph is better suited for the study of focal cerebral ischemia than the conventional stationary detectors because superposition of tissue layers is avoided.

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