[以Mini-Lewe迷你猪为模型的新生儿肾脏移植]。

P Althaus, H Oesterwitz, A Berkes, D Fahlenkamp, B Schulz, M Mebel
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引用次数: 0

摘要

新生儿供体肾脏在移植中的重要性尚未明确定义。本研究的目的是研究成年受体新生肾脏的形态和功能适应程度。7只Lewe迷你猪幼犬(年龄:3-4周)的mls匹配的肾脏被整体移植到立即双侧肾切除术的母亲身上。初步结果表明,动脉血管和血液供应是限制新生供肾成人受体适应的因素。
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[Transplantation of the kidneys from newborn donors, using the Mini-Lewe minipig as a model].

The importance of kidneys from newborn donors in transplantation has not been clearly defined. The purpose of this study was to investigate the degree of morphological and functional adaptation of the newborn kidney in an adult recipient. 7 MLS-matched kidneys from Lewe minipig puppies (age: 3-4 weeks) had been transplanted en bloc to their mothers with immediately bilateral nephrectomy. Preliminary results suggested that arterial vasculature and blood supply are the limiting factors in adaptation of newborn donor kidneys in adult recipients.

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