左心室功能。用PEEP对犬进行人工通气的研究[作者简介]。

Anesthesie, analgesie, reanimation Pub Date : 1981-01-01
A Net, G Vazquez, S Benito, A Artigas, R Martinez, M I Quintana
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引用次数: 0

摘要

根据Powers等人提出的假说,在人工通气患者增加PEEP时,心内血管可能会塌陷。因此,心肌缺血可以解释为什么有些人会出现左心室衰竭的迹象。为了验证这个推理是否正确,我们测量了正常狗的LVEDP,这些狗的PEEP升高到40 cm H2O。我们的结果似乎指向以下结论:a)在正常犬中,斯塔林关系没有改变,保持在相同的超收缩模式内。b)随着PEEP的增加,在30 cm H2O时心室功能保持在同一曲线内,在40 cm H2O时心室收缩力曲线上升。所有这些都表明,在我们的实验条件下,假设由于PEEP影响而存在左心室衰竭似乎是不合理的。
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[Left ventricular function. Study during artificial ventilation with PEEP in the dog (author's transl)].

According to Powers et collaborators the hypothesis that intramyocardial vessels may be collapsed in artificially ventilated patient with added PEEP, could be arisen. So, myocardial ischemia may explain why in some of those ones there appear signs of left ventricular failure. To test whether this reasoning was correct we measured LVEDP in normal dogs submitted to increasing levels of PEEP up to 40 cm H2O. Our results seem to point towards the following conclusions: a) In normal dogs, Starling relation is not altered and remains within the same hypercontractility pattern. b) As PEEP increases, ventricular function remains within the same curve up to 30 cm H2O and jumps to a higher contractility curve at 40 cm H2O of PEEP. All of this would suggest that under our experimental conditions it does not seem reasonable to assume the existence of left ventricular failure due to PEEP influence.

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