小鼠胚胎肾的绒毛膜-尿囊膜移植。一种改进的肾脏形态发生体外研究技术。

Investigative urology Pub Date : 1981-03-01
G M Preminger, W F Koch, F A Fried, J Mandell
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引用次数: 0

摘要

以往体外器官培养技术对胚胎肾脏发育的实验研究受到外植体存活时间短的限制。利用鸡绒毛膜尿囊膜移植未分化的小鼠肾脏雏形,可以使移植物血管化,并具有较早的成熟和早期肾单位的出现。
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Chorioallantoic membrane grafting of the embryonic murine kidney. An improved in vitro technique for studying kidney morphogenesis.

Previous experimental investigations of embryonic kidney development with in vitro organ culture techniques have been limited by the short duration of explant viability. Utilization of chick chorioallantoic membranes for transplanting undifferentiated murine kidney rudiments has allowed vascularization of the grafts with advanced maturation and the appearance of early nephron units.

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