[病毒对伽马辐射的敏感性(作者译)]。

H Mahnel, H Stettmund von Brodorotti, K Ottis
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引用次数: 0

摘要

用8种低浓度悬浮在饮用水中的病毒和4种高浓度悬浮在组织培养基中的病毒,比较了病毒对伽马射线的敏感性。结果表明,以下因素是病毒对伽马射线产生抗性的原因:病毒类型:特异抗辐射能力差异较大;总的来说,与病毒对化学-物理影响的总体抗性的相关性比与所检测病毒的核酸类型的相关性更密切;2. 悬浮介质和聚集状态:高蛋白质含量和冻干大大增加了对伽马射线的抵抗力;3.病毒浓度:与病毒含量低的悬浮液相比,病毒浓度高的悬浮液中的病毒减少了10倍,需要更高的辐射剂量。结果表明,失活动力学为一级反应。温度升高到41摄氏度没有显示出任何显著的影响。
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[Sensitiveness of viruses fo gamma radiation (author's transl)].

The sensitiveness of viruses to gamma rays was compared using eight viruses suspended with low concentration in drinking water, and four viruses present in high concentrations in tissue culture medium. The results show that the following factors are responsible for the resistance of viruses to gamma rays: 1. type of virus: the specific radiation resistance varied considerably; in general, there was a closer correlation with the general resistance of the virus to chemico-physical influences than with the type of nucleic acid of the virus examined; 2. medium of suspension and state of aggregation: high protein content and lyophilisation increased the resistance to gamma rays widely; 3. virus concentration: the virus reduction by a factor of 10 in suspensions with high virus concentration needed a higher radiation dose compared with suspensions of low virus content. All the results demonstrate the kinetics of inactivation to be a 1st order reaction. The increase of temperature to 41 degrees C did not show any significant influence.

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