{"title":"锂对人体有诱变作用吗?","authors":"N Banduhn, G Obe, B Müller-Oerlinghausen","doi":"10.1055/s-2007-1019634","DOIUrl":null,"url":null,"abstract":"<p><p>Peripheral blood lymphocytes of 77 patients under lithium-therapy were analyzed with respect to structural chromosomal aberrations. As compared to controls not treated with lithium, no elevation of the frequencies of chromosomal aberrations was found in the patients. Comparable investigations may lead to erroneous conclusions if the higher X-ray load of psychiatric patients is not considered.</p>","PeriodicalId":76325,"journal":{"name":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","volume":"13 4","pages":"218-27"},"PeriodicalIF":0.0000,"publicationDate":"1980-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1055/s-2007-1019634","citationCount":"17","resultStr":"{\"title\":\"Is lithium mutagenic in man?\",\"authors\":\"N Banduhn, G Obe, B Müller-Oerlinghausen\",\"doi\":\"10.1055/s-2007-1019634\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Peripheral blood lymphocytes of 77 patients under lithium-therapy were analyzed with respect to structural chromosomal aberrations. As compared to controls not treated with lithium, no elevation of the frequencies of chromosomal aberrations was found in the patients. Comparable investigations may lead to erroneous conclusions if the higher X-ray load of psychiatric patients is not considered.</p>\",\"PeriodicalId\":76325,\"journal\":{\"name\":\"Pharmakopsychiatrie, Neuro-Psychopharmakologie\",\"volume\":\"13 4\",\"pages\":\"218-27\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1055/s-2007-1019634\",\"citationCount\":\"17\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pharmakopsychiatrie, Neuro-Psychopharmakologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-2007-1019634\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmakopsychiatrie, Neuro-Psychopharmakologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-2007-1019634","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Peripheral blood lymphocytes of 77 patients under lithium-therapy were analyzed with respect to structural chromosomal aberrations. As compared to controls not treated with lithium, no elevation of the frequencies of chromosomal aberrations was found in the patients. Comparable investigations may lead to erroneous conclusions if the higher X-ray load of psychiatric patients is not considered.
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