术后是否也存在“晚期”甲状旁腺功能减退?

P Potestà, R Murolo, S Costantini, G Imperoli, F Giardina, G Guerriero
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引用次数: 0

摘要

颈部手术后甲状旁腺功能减退症,主要是甲状腺切除术,并不是一个罕见的事件,众所周知,多年来。术后甲状旁腺功能减退可表现为两种不同病因和预后的临床症状。第一种疾病是一种短暂的甲状旁腺功能减退症,可能在几周或几个月内自行恢复。第二种疾病是永久性甲状旁腺功能减退,需要明确的根尖治疗。无论如何,在这两种情况下,低钙症状总是在手术后很短的时间内开始,通常是在几天到几个月的无症状期之后。只有少数病例甲状旁腺功能减退症在手术多年后临床发生。描述一个病人的甲状旁腺功能减退症,成为临床上明显的甲状腺手术三十年后,在此描述。我们的研究结果和对医学文献报道的一些病例的回顾,可以提示第三种形式的术后甲状旁腺功能减退,其独特的特征是很晚才开始,可能是长期潜伏的甲状旁腺功能不全。
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Does it exist also a "late" post-surgical hypoparathyroidism?

Hypoparathyroidism following neck surgery, mainly thyroidectomy, is not a rare event, well known since many years. Post-surgical hypoparathyroidism may occur in form of two clinical syndromes of different etiology and prognosis. The first disease is a transitory hypoparathyroidism that might spontaneously recover within a few weeks or months. The second disease is a permanent hypoparathyroidism needing a definitive opoterapic treatment. Anyhow in both cases, hypocalcemic symptoms begin always within a short time from surgery, usually after an asymptomatic period elapsing from days to months. Only few cases of hypoparathyroidism clinically conclamate after many years from surgery have been reported. Description of a patient with hypoparathyroidism that became clinically evident thirty years after the thyroid surgery is herewith described. Our findings and review of a few cases reported by medical literature, can suggest a third form of post-surgical hypoparathyroidism with the distinctive feature of a very late beginning, probably following a long period of a latent parathyroid insufficiency.

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