【口腔鳞状细胞癌的统计分析】。

G S Chen, C H Chen
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摘要

口腔鳞状细胞癌是口腔最常见的恶性肿瘤,约占口腔恶性肿瘤的90%。我们回顾性分析1987年至1991年间在高雄医学院附属医院经组织病理检查证实的口腔鳞状细胞癌211例。男性194人,女性17人,男女比例为11.4比1。患者年龄23 ~ 95岁,平均51.96岁,40 ~ 59岁发病率最高(63.3%)。鳞状细胞癌最常见于颊黏膜。发生在颊黏膜的病例占40.8%,舌头占25.6%,下颌骨占17.1%,上颌骨占9.5%,下唇占5.2%,口腔底占1.9%。对195例病历中有生活习惯记录的患者进行了习惯、患者年龄和肿瘤发生部位之间的关系评估。我们使用一般因子方差分析来检验习惯和患者年龄之间的关系。采用层次线性分析来确定习惯与受累肿瘤位置之间是否存在关联。195例中有144例(73.85%)经常咀嚼槟榔。有咀嚼槟榔习惯患者的平均年龄(49.04岁)明显低于无咀嚼槟榔习惯患者(59.27岁)(p = 0.006)。(摘要删节250字)
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[A statistical analysis of oral squamous cell carcinoma].

Oral squamous cell carcinoma is the most common malignant tumor of the oral cavity, and it accounts for about 90% of malignant oral tumors. We have retrospectively reviewed 211 patients with oral squamous cell carcinoma which were confirmed by histopathological examination at Kaohsiung Medical College Hospital in the period between 1987 and 1991. There were 194 males and 17 females, with a male to female ratio of 11.4 to 1. The age of the patients ranged from 23 to 95 years, mean 51.96 years, with the greatest incidence of disease in the ages between 40 and 59 years (63.3%). Squamous cell carcinoma occurred most often on the buccal mucosa. There were 40.8% of cases which occurred on the buccal mucosa, 25.6% on the tongue, 17.1% on the gingiva of mandible, 9.5% on the maxilla, 5.2% on the lower lip and 1.9% on the floor of mouth. 195 cases with a recorded history of habits in the patient's medical records were evaluated for the relationships between habits, patient's age and the location of the tumor involved. We have used a general factorial ANOVA to examine the relationship of habits and patients' age. A Hierarchical Loglinear Analysis was used to determine whether there was an association between habits and the location of tumor involved. Of the 195 cases, 144 (73.85%) chewed betel nut regularly. The mean age of the patients with betel nut chewing habits (49.04 years) was significantly younger than that of the patients without betel nut chewing habits (59.27 years) (p = 0.006).(ABSTRACT TRUNCATED AT 250 WORDS)

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