干扰素作用中的信号转导机制(简要综述)。

Acta microbiologica Hungarica Pub Date : 1993-01-01

G Premecz, A Markovits, I Földes

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引用次数: 0

摘要

实验结果表明，蛋白激酶C (PK-C)可能在IFNs的作用中发挥重要作用，但确切的生化途径尚不清楚。最近的证据揭示了ifn作用机制的复杂性，并表明ifn - α， - β和- γ诱导通路是重叠的。我们简要地讨论了在这个领域中已知的情况，并提出了一种方法，可以调和不同的观点。

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Signal transducing mechanisms in interferon action (a brief review).

Experimental results suggest that protein kinase C (PK-C) may play a substantial role in the action of IFNs, but the precise biochemical pathway remains unknown. Recent evidences reveal the complexity of the mechanism of IFN-action and show that the IFN-alpha, -beta and -gamma induced pathways are overlapping. We briefly discuss what is known in this field and suggest a way in which the contrasting views might be reconciled.

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Acta microbiologica Hungarica

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