重金属增强硝酸处理的腺病毒在HeLa细胞中的再活化

Mutation Research Letters Pub Date : 1995-01-01 DOI:10.1016/0165-7992(95)90063-2

S.M. Piperakis

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引用次数: 1

摘要

用氯化镉和氯化锌处理HeLa细胞可提高硝酸处理腺病毒2 (ade2)的存活率。如果细胞处理和病毒感染之间的时间间隔延迟36小时，这种增加是最大的。诱导过程只需要在处理后的3小时内合成蛋白质;如果在此时间后将环己亚胺添加到细胞中，则不会阻止增强再激活的表达。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Heavy metals enhance the reactivation of nitrous acid-treated adenovirus in HeLa cells

Treatment of HeLa cells with cadmium chloride and zinc chloride increases the survival rate of nitrous acid-treated adenovirus 2 (ade2). This increase is maximal if the time interval between cell treatment and virus infection is delayed by 36 h. The induction process requires protein synthesis only during the 3-h period immediately following treatment; cycloheximide does not prevent the expression of enhanced reactivation if added to the cells after this time.

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Mutation Research Letters

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