年轻人的直肠癌。[约38例]。

S Nadir, A Chlihi, M Alyoune, R Alaoui, R Ismail, D Jamil, A Cherkaoui
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引用次数: 0

摘要

本回顾性研究基于1978年1月至1993年12月15年间收集的38例25岁以下年轻人直肠癌病例。患者平均年龄23岁(14 ~ 25岁),性别比2.1。组织学表现为高分化腺癌12例,中、微分化及未分化癌14例,胶体癌10例,绒毛状肿瘤伴恶性改变2例。只有11例患者可以进行根治性手术切除。16名患者接受了姑息治疗,12名拒绝手术。3例内脏转移患者未提出治疗方案。仅有11例患者可以随访,平均5年生存率为10%。年轻人直肠癌的预后很差,因为在晚期诊断较晚,并且遇到了侵袭性的组织学形式。
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[Cancer of the rectum in young adults. Apropos of 38 cases].

This retrospective study is based upon 38 cases of rectal carcinomas occurring in young individuals aged under 25, collected during the 15 year period from January 1978 to December 1993. The mean age of the patients was 23 (range: 14 to 25), with a gender ratio of 2.1. Histology revealed a well differentiated adenocarcinoma in 12 cases, a moderately or slightly differentiated and undifferentiated carcinoma in 14 cases, a colloid carcinoma in 10 cases and a villous tumor with malignant change in 2 cases. Curative surgical excision was possible in only 11 patients. Sixteen patients underwent a palliative procedure, while 12 refused surgery. No treatment was proposed to 3 patients with visceral metastases. Only 11 patients could be followed up, with a mean 5-year survival rate of 10%. The prognosis of rectal carcinoma in young individuals is poor because of late diagnosis at an advanced stage and the aggressive histologic forms encountered.

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