癌症患者尿锌排泄与急性期反应。

The clinical investigator Pub Date : 1994-12-01 DOI:10.1007/BF00577746

B Melichar, P Jandik, M Tichy, F Malir, J Mergancova, Z Voboril

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引用次数: 8

摘要

我们研究了55例实体瘤患者和20例对照患者的尿锌和血清c反应蛋白、α -1酸性糖蛋白、接触珠蛋白、转铁蛋白和白蛋白前的水平。肿瘤患者尿锌、血清c反应蛋白、α -1酸性糖蛋白和触珠蛋白均显著升高，血清前白蛋白显著降低。尿锌与c反应蛋白、α -1酸性糖蛋白、触珠蛋白呈显著正相关，与转铁蛋白、前白蛋白呈显著负相关。癌症患者的高锌血症似乎与急性期反应有关。我们的数据提供了进一步的证据，表明尿锌排泄增加与全身炎症反应有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Urinary zinc excretion and acute phase response in cancer patients.

We investigated urinary zinc and serum levels of C-reactive protein, alpha-1 acid glycoprotein, haptoglobin, transferrin and prealbumin in 55 patients with solid tumors and 20 controls. Urinary zinc, serum C-reactive protein, alpha-1 acid glycoprotein and haptoglobin were significantly higher, and serum prealbumin was significantly lower in cancer patients. A significant positive correlation between urinary zinc and C-reactive protein, alpha-1 acid glycoprotein and haptoglobin, as well as a negative correlation with transferrin and prealbumin were observed. Hyperzincuria in cancer patients appears to be linked to the acute phase response. Our data provide further evidence implicating systemic inflammatory response in increased urinary zinc excretion.

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