某大学社区乙型肝炎病毒感染的血清流行病学研究

G.E.N Pub Date : 1994-07-01
G González, A Viamonte, C Pérez-Maldonado
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引用次数: 0

摘要

乙型肝炎病毒(HBV)感染实际上是世界范围内的一个主要问题,主要是因为它引起的慢性和急性感染的发病率很高。为了确定洛斯安第斯大学生物分析学院的HBV发病率,我们使用ELISA方法研究了HBV标记物的存在:表面抗原(HBsAg)和抗核心(a-HBc),随机选择167名受试者,由135名上学期的学生,12名教授和20名来自生物化学,血液学和免疫学领域的员工组成。在所有检测样本中,19例(11.4%)的任一标记物呈阳性,3例(1.8%)为HBsAg阳性,16例(10.2%)为a-HBc阳性。只有一个样本对两种标记都呈阳性。性行为阳性率为9.1%,输血阳性率为16.7%,早期肝炎阳性率为18.2%。
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[Seroepidemiological study of hepatitis B virus infection in a university community].

The hepatitis B virus (HBV) infection is actually a major problem worldwide, due mainly to the high incidence of chronic and acute infection it causes. In order to determinate the HBV incidence in the School of Bioanalysis of the University of Los Andes, we studied the presence of the HBV markers: surface antigen (HBsAg) and anti-Core (a-HBc) by using an ELISA method in randomly selected population of 167 subjects composed by 135 students of the last semester, 12 professors, and 20 employees from the Biochemistry, Haematology, and Immunology's areas. Of all the examined samples, 19 (11.4%) were positive for any of the markers, 3 (1.8%) for HBsAg and 16 (10.2%) for a-HBc. Only one sample was positive for both markers. The posivity was solely observed in the students group were 9.1% were sexually active, 16.7% received blood transfusions and 18.2% suffered early hepatitis.

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[Hepatitis C virus]. [Evaluation of methods for the diagnosis of Helicobacter pylori infection]. [Leptospirosis in Gastroenterology. Study of 14 cases in the Hospital Universitário de Caracas 1984-1994]. [Gastrointestinal stromal sarcoma. Report of a case and review of the literature]. [Von Recklinghausen disease and hepatic neurofibromatosis].
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