[新生儿复发性皮肤疱疹与阿昔洛韦]。

Pediatrie Pub Date : 1993-01-01
J Haddad, V Pierrat, B Langer, S Rousseau, D Astruc, J Messer, P Lequien
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引用次数: 0

摘要

作者报告了两例新生儿单纯疱疹病毒2型(HSV2)感染后发生的皮肤复发性疱疹,并对阿昔洛韦(ACV)急性或抑制性治疗的作用进行了评论。这两名婴儿在新生儿期后未接受ACV治疗。无复发性皮肤疱疹发作后继发病毒性传播。Bergström等人报道的一个儿童皮肤疱疹后发生HSV2脑炎复发的病例主张在复发性疱疹中使用ACV。然而,ACV可能会改变新生儿和儿童对HSV2感染的宿主防御反应。因此,目前似乎还不推荐使用ACV作为复发性皮肤疱疹的急性或抑制性治疗,除非注意到病毒性疾病的进展。
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[Recurrent cutaneous herpes in the newborn and acyclovir].

The authors report two cases of cutaneous recurrent herpes occurring after a neonatal herpes simplex virus type 2 (HSV2) infection and comment on the role of acute or suppressive therapy by aciclovir (ACV). The two infants were not treated by ACV after the neonatal period. None of the recurrent cutaneous herpes episodes was followed by viral widespread. One case reported by Bergström et al on a relapse of HSV2 encephalitis occurring after a cutaneous herpes in a child argues for the use of ACV in recurrent herpes. However, ACV might alter host defense response to HSV2 infection in neonates and children. Thus, it seems not yet recommended to use ACV either as acute or suppressive therapy in recurrent cutaneous herpes unless a progression of the viral disease is noted.

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