他卡尔西醇软膏治疗牛皮癣。

M Nishimura, Y Makino, H Matugi
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引用次数: 0

摘要

采用无毛大鼠皮肤和人皮肤,研究了含2微克/克的他骨化醇软膏的透皮吸收。在动物实验中,大量的他骨糖醇被经皮吸收,而在人体皮肤的情况下,这种化合物几乎没有被吸收。安慰剂对照双盲右/左比较证实,这种软膏是有效和安全的治疗牛皮癣。
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Tacalcitol ointment for psoriasis.

Transdermal absorption of tacalcitol from the ointment containing 2 micrograms/g was studied using hairless rat and human skin. In the animal experiments, a non-negligible amount of tacalcitol was absorbed transdermally, whereas in the case of human skin, this compound was hardly absorbed at all. A placebo-controlled double-blind right/left comparison confirmed that this ointment is effective and safe for the treatment of psoriasis.

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