发生在阴茎扁平苔藓内的鳞状细胞癌。莫氏显微手术治疗。

S Leal-Khouri, G J Hruza
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引用次数: 42

摘要

背景:扁平苔藓是一种常见病,低恶性潜能。在文献中有几个病例报告鳞状细胞癌(SCC)发展为皮肤扁平苔藓。然而,阴茎扁平地衣发生鳞状细胞癌是极为罕见的。目的:报告1例阴茎扁平地衣发生的鳞状细胞癌,探讨莫氏显微手术治疗方法,并复习文献。方法:病理活检诊断为扁平苔藓和鳞状细胞癌。结果:我们报告了英文文献中首例SCC在阴茎扁平苔藓内发生的病例。经Mohs手术治疗,术后2年患者阴茎功能正常,无肿瘤。结论:扁平苔藓内可能发生鳞状细胞癌。治疗抵抗的长期扁平苔藓病例应进行活检。莫氏显微手术是一种精确的治疗阴茎鳞状细胞癌,它避免了阴茎切除术,并保留了正常的功能。
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Squamous cell carcinoma developing within lichen planus of the penis. Treatment with Mohs micrographic surgery.
BACKGROUND Lichen planus is a common disease, with a low malignant potential. There are several case reports in the literature of squamous cell carcinoma (SCC) developing in cutaneous lichen planuse. However, SCC developing in penile lichen planus is extremely rare. OBJECTIVE To report a case of SCC developing within penile lichen planus, to discuss treatment with Mohs micrographic surgery, and to review the literature. METHOD The diagnosis of lichen planus and SCC were made by biopsy of the lesion. RESULTS We present the first case in the English literature of SCC developing within lichen planus of the penis. The lesion was treated with Mohs surgery and the patient's penis is functional and free of tumor 2 years postoperatively. CONCLUSION Squamous cell carcinoma may develop within lichen planus. Treatment-resistant longstanding cases of lichen planus should be biopsied. Mohs micrographic surgery is a precise treatment for penile SCC, it avoids penectomy, and preserves normal function.
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