{"title":"百草枯引起慢性眼表毒性。","authors":"K Vlahos, M Goggin, D Coster","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>We describe a case of topical exposure to a commercial solution of paraquat. Chronic, severe ocular surface destruction resulted, probably due to absorption of the herbicide into the surface tissues, facilitated by a surfactant present in the preparation, and to intracellular redox cycling of the paraquat cation. Ocular paraquat toxicity is described and explained in the context of the toxicity of systemic absorption.</p>","PeriodicalId":8596,"journal":{"name":"Australian and New Zealand journal of ophthalmology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1993-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Paraquat causes chronic ocular surface toxicity.\",\"authors\":\"K Vlahos, M Goggin, D Coster\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We describe a case of topical exposure to a commercial solution of paraquat. Chronic, severe ocular surface destruction resulted, probably due to absorption of the herbicide into the surface tissues, facilitated by a surfactant present in the preparation, and to intracellular redox cycling of the paraquat cation. Ocular paraquat toxicity is described and explained in the context of the toxicity of systemic absorption.</p>\",\"PeriodicalId\":8596,\"journal\":{\"name\":\"Australian and New Zealand journal of ophthalmology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Australian and New Zealand journal of ophthalmology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Australian and New Zealand journal of ophthalmology","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
We describe a case of topical exposure to a commercial solution of paraquat. Chronic, severe ocular surface destruction resulted, probably due to absorption of the herbicide into the surface tissues, facilitated by a surfactant present in the preparation, and to intracellular redox cycling of the paraquat cation. Ocular paraquat toxicity is described and explained in the context of the toxicity of systemic absorption.