[Use of diffusion methods in the determination of sensitivity of medically important micromycetes].

The authors evaluated the sensitivity of 35 strains of mycotic agents to eight antifungal preparations, using two methods: the diffuse disc test and the method of assessment of the MIC in a liquid medium. On comparison of results obtained by the two methods they reached the conclusion that the diffuse disc method makes possible only orientation as regards sensitivity and does not fully correlate with the results of MIC. Some strains with MIC values at the sensitivity level seemed resistant according to the disc test. From a total of seven agar media used for the disc test only two were suitable: the medium with casitone and Sabouraud's glucose agar. In particular on the former there were inhibition zones round the discs which were easiest to evaluate and which were constant at different incubation temperatures.