准分子激光照射的光消融——微神经外科的合适概念?

H J König, G Bücker, A Stefanec, U Hiller, F Gullotta
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引用次数: 2

摘要

通过动物实验研究了准分子激光束在显微神经外科手术中的适用性。用193nm氟化氩、248nm氟化氪、308 nm氯化氙和351nm氟化氙辐照大鼠颅骨、皮质和坐骨神经。存活时间长达30天后,研究上述组织中激光病变的显微镜和电子光学结果。通过准分子激光束,在任何期望的穿透或延伸深度下,对周围组织没有或只有低热损伤,产生高精度的组织效应。与从动物实验中获得的经验类似,讨论了在切除颅神经或血管结构周围的骨组织,癫痫灶,或在疼痛手术中切断通路(例如脊髓神经背根进入区)的可能用途。
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[Photoablation using Excimer laser irradiation--a suitable concept for microneurosurgery?].

The suitability of Excimer laser beam for microneurosurgery was investigated in an animal experimental study. Cranial bones, cortex and the nervus ischiadicus of the rat were irradiated with 193 nm argon fluoride, 248 nm krypton fluoride, 308 nm xenon chloride and 351 nm xenon fluoride. After survival times of up to 30 days microscopic and electron optic findings of laser lesions at the tissues mentioned above, were studied. By means of the Excimer laser beam high precision tissue effects without or with only low thermal damage to the surrounding tissue were produced with any desired depth of penetration or extension. In analogy with the experiences gathered from animal experiments, a possible use is discussed for the removal of bone tissue around cranial nerves or vascular structures, of epileptogenic foci, or for cutting off pathways in pain surgery (e.g. the zone of entry of the dorsal root of spinal nerves).

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