优化小鼠腹水单克隆抗体的体内生产。

NIPH annals Pub Date : 1993-06-01
P Lausund, E Paus, K Ingebrigtsen
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引用次数: 0

摘要

该说明简要介绍了国家公共卫生研究所用于在小鼠腹水中生产单克隆抗体的方法。这种获得大量单克隆抗体的方法被广泛使用。改进体内方法和提高每只小鼠的产量可以减少使用的动物数量。
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Optimalized in vivo production of monoclonal antibodies in mouse ascitic fluid.

The note contains a brief summary of the method in use at the National Institute of Public Health for the production of monoclonal antibodies in mouse ascitic fluid. This method of obtaining large amounts of monoclonal antibodies is widely used. Refining the in vivo method and increasing the yield from each mouse could result in a reduction of the number of animals used.

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Optimalized in vivo production of monoclonal antibodies in mouse ascitic fluid. Time variations in injury incidence. Sogn and Fjordane county community-based injury prevention: evaluation design. Observations on Pseudomonas aeruginosa proteolytic and toxic activity in experimentally infected rats. Abstracts of the Norwegian Virology Symposium IV. Ustaoset, March 19-20, 1992.
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