{"title":"氧自由基，是进化的失败还是成功?","authors":"G Barja","doi":"10.3109/10715769309147343","DOIUrl":null,"url":null,"abstract":"<p><p>Oxygen radicals are no doubt involved in the development of many pathological states. Nevertheless, the possibility that oxygen radical production was selected for during biological evolution in order to perform useful roles in relation to cellular metabolism is contemplated; previous data on this subject are briefly reviewed. The concept of an \"oxygen radical cycle\" is proposed as a useful theoretical model.</p>","PeriodicalId":12438,"journal":{"name":"Free radical research communications","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10715769309147343","citationCount":"52","resultStr":"{\"title\":\"Oxygen radicals, a failure or a success of evolution?\",\"authors\":\"G Barja\",\"doi\":\"10.3109/10715769309147343\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Oxygen radicals are no doubt involved in the development of many pathological states. Nevertheless, the possibility that oxygen radical production was selected for during biological evolution in order to perform useful roles in relation to cellular metabolism is contemplated; previous data on this subject are briefly reviewed. The concept of an \\\"oxygen radical cycle\\\" is proposed as a useful theoretical model.</p>\",\"PeriodicalId\":12438,\"journal\":{\"name\":\"Free radical research communications\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3109/10715769309147343\",\"citationCount\":\"52\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Free radical research communications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3109/10715769309147343\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Free radical research communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3109/10715769309147343","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Oxygen radicals, a failure or a success of evolution?
Oxygen radicals are no doubt involved in the development of many pathological states. Nevertheless, the possibility that oxygen radical production was selected for during biological evolution in order to perform useful roles in relation to cellular metabolism is contemplated; previous data on this subject are briefly reviewed. The concept of an "oxygen radical cycle" is proposed as a useful theoretical model.
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