V V Ptushkin, G D Selidovkin, K L Chimishkian, V B Larionova, Iu V Chervonobab, D M Mkheidze, S M Portnoĭ, S A Tiulndin
{"title":"[外周血自体造血干细胞移植在高剂量化疗后血液肿瘤和实体肿瘤患者中的应用]。","authors":"V V Ptushkin, G D Selidovkin, K L Chimishkian, V B Larionova, Iu V Chervonobab, D M Mkheidze, S M Portnoĭ, S A Tiulndin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Peripheral mononuclears under normal hemopoiesis and after chemotherapy or/and cytokin were isolated on blood cell separator and cryopreserved. The cells from 22 patients with different hematological and solid malignancies were examined. Mononuclears with high content of hemopoiesis precursors may be collected rapidly after stimulation. Fast and persistent recovery of hemopoiesis in transplantation of this material after superhigh-dose chemotherapy of prognostically unfavourable patients is demonstrated. Cytokin (granulocytic and granulocytic-macrophagal growth factors) promoted fast and reliable production of sufficient quantities of peripheral blood hemopoiesis cells precursors.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 1","pages":"9-13"},"PeriodicalIF":0.2000,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Use of autologous hematopoietic stem cells from peripheral blood for transplantation in patients with hematologic and solid neoplasms after high-dose chemotherapy].\",\"authors\":\"V V Ptushkin, G D Selidovkin, K L Chimishkian, V B Larionova, Iu V Chervonobab, D M Mkheidze, S M Portnoĭ, S A Tiulndin\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Peripheral mononuclears under normal hemopoiesis and after chemotherapy or/and cytokin were isolated on blood cell separator and cryopreserved. The cells from 22 patients with different hematological and solid malignancies were examined. Mononuclears with high content of hemopoiesis precursors may be collected rapidly after stimulation. Fast and persistent recovery of hemopoiesis in transplantation of this material after superhigh-dose chemotherapy of prognostically unfavourable patients is demonstrated. Cytokin (granulocytic and granulocytic-macrophagal growth factors) promoted fast and reliable production of sufficient quantities of peripheral blood hemopoiesis cells precursors.</p>\",\"PeriodicalId\":50427,\"journal\":{\"name\":\"Gematologiya I Transfuziologiya\",\"volume\":\"41 1\",\"pages\":\"9-13\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"1996-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gematologiya I Transfuziologiya\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gematologiya I Transfuziologiya","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"HEMATOLOGY","Score":null,"Total":0}
[Use of autologous hematopoietic stem cells from peripheral blood for transplantation in patients with hematologic and solid neoplasms after high-dose chemotherapy].
Peripheral mononuclears under normal hemopoiesis and after chemotherapy or/and cytokin were isolated on blood cell separator and cryopreserved. The cells from 22 patients with different hematological and solid malignancies were examined. Mononuclears with high content of hemopoiesis precursors may be collected rapidly after stimulation. Fast and persistent recovery of hemopoiesis in transplantation of this material after superhigh-dose chemotherapy of prognostically unfavourable patients is demonstrated. Cytokin (granulocytic and granulocytic-macrophagal growth factors) promoted fast and reliable production of sufficient quantities of peripheral blood hemopoiesis cells precursors.
期刊介绍：
The journal publishes original theoretical and clinical studies, lectures, reviews, and practical notes concerning various problems of hematology and clinical and industrial transfusion. The journal provides information on the etiology, pathogenesis, diagnosis and treatment of blood disorders as well as on related non-hematological conditions (internal diseases, poisoning, exposure to ionizing radiation etc.).
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