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引用次数: 0

摘要

根据结构和功能的研究,将动物凝集素分为依赖钙离子的c型和不依赖钙而依赖硫醇的s型两类。在这一后期,一组被广泛研究为S-Lac型。它们是用添加了乳糖的盐水缓冲液在硫醇试剂的存在下提取的,构成了一个包含一系列保守氨基酸的结构相关蛋白家族。它们特异性结合互补的糖缀合物,其生物合成和定位受发育调控。它们的作用可能与不同器官的几种生物活性有关。
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[Soluble beta-galactoside-binding lectins].

Animal lectins are classified on the basis of structural and functional studies in two types: the C-type, characterized by their dependence on calcium ions and the S-type which are not calcium-dependent, but thiol-dependent. In this late one, a group has been extensively studied as the S-Lac type. They are extracted with saline buffers added with lactose in presence of thiol agents, and constitute a family of structurally related protein which contain a series of conserved amino acids. They specifically bind to complementary glicoconjugates, and their biosynthesis and localization are developmentally regulated. Their role could be related to several biological activities in different organs.

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