超声骨密度计测定正常孕妇的骨密度。

Nihon Sanka Fujinka Gakkai zasshi Pub Date : 1996-11-01
K Tamura, T Akiyama, A Taguchi, H Fujikawa, H Saitoh, T Yanaihara
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引用次数: 0

摘要

采用超声骨密度仪(Achilles, Luner Co, USA)测定育龄妇女和孕妇的骨密度。育龄妇女Os骨密度、声速(SOS)和广谱超声衰减(BUA)参数与双能x线吸收仪(DXA)测定的腰2-4骨密度均有显著相关性(p < 0.01)(平均年龄;24.5 +/- 2.3, n = 30)。研究了妊娠和分娩期间骨密度的变化。在横断面研究中,未观察到SOS、BUA和僵硬度的显著变化,但在纵向研究中(n = 21),所有这些参数都随着妊娠的进展而下降。骨转换指标(血清钙、碱性磷酸酶、前胶原1-C型肽、尿钙/铬和脱氧吡啶啉/铬)在妊娠期间没有变化。10例孕妇骨密度低(SD平均值小于1.5)。骨密度低与正常孕妇的骨转换指标无显著差异。建议对育龄妇女和孕妇进行骨密度筛查,以发现骨质减少症。
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[Measurement of bone density by ultrasound bone densitometer in normal pregnant women].

The bone mineral density in reproductive aged and pregnant women was measured with an ultrasound bone densitometer (Achilles, Luner Co, USA). Both parameters of bone density on Os calsis, sound of speed (SOS) and broad ultrasound attenuation (BUA) were significantly correlated with bone mineral density in lumbar2-4 measured by dual energy X-ray absorptiometry (DXA) (p < 0.01) in reproductive aged women (mean age; 24.5 +/- 2.3, n = 30). The changes in bone density during pregnancy and at delivery were studied. In a cross-sectional study, no significant changes in SOS, BUA and stiffness were observed, but in a longitudinal study (n = 21), all of these parameters decreased as pregnancy advanced. The markers of bone turnover (serum Ca, alkaline phosphatase, procollagen type 1-C peptide, urinary Ca/Cr and deoxypyridinoline/Cr) did not change during pregnancy. Ten pregnant women with low bone density (less than-1.5 SD mean value) were found. There was no significant difference between the markers of bone turnover in pregnant women with low and normal bone density. The clinical usefulness of the screening of bone density of reproductive aged and pregnant women to detect osteopenia is suggested.

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