Paul J. Harrison , Wendy H. Wighton-Benn , Josephine M. Heffernan , Maurice W. Sanders , R.Carl A. Pearson
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Amyloid Precursor Protein mRNAs in Alzheimer's Disease
Hybridization studies of mRNA link genetic with neurochemical and neuropathological approaches to Alzheimer's disease (AD). Here we review the distribution and abundance of amyloid precursor protein mRNAs in normal and AD-afflicted brains. The expression of apolipoprotein E and presenilin mRNAs are also discussed.