[头孢醌治疗急性牛乳腺炎的贡献]。

Tierarztliche Praxis Pub Date : 1997-05-01
N Y Shpigel, P Schmid
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引用次数: 0

摘要

头孢醌是第四代用于兽药的头孢菌素类抗生素。一项欧洲多中心研究确定了这种现代抗菌药物对广泛的牛病原体的高体外活性。即使在非常低的活性成分浓度下,革兰氏阳性和革兰氏阴性乳腺炎药物也被灭活,包括通常对其他药物耐药的肠杆菌科。以实验性大肠杆菌乳腺炎为例的临床试验结果证明了头孢醌在体内的有效性。与使用同样具有良好体外活性的对照药物的常规治疗相比,以1 mg/kg体重剂量率的肠外给药产生了明显更好的治疗效果。
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[Contribution to the treatment of acute bovine mastitis with cefquinome].

Cefquinome is the first 4th generation cephalosporin antibiotic developed for use in veterinary medicine. A European multicentre study established a high in vitro activity for this modern antimicrobial drug against a wide spectrum of bovine pathogens. Gram-positive and gram-negative mastitis agents were inactivated even at very low active ingredient concentrations, including Enterobacteriaceae which are often resistant to other drugs. The results of clinical trials using experimental E. coli mastitis as an example demonstrate the efficacy of cefquinome in vivo. Parenteral administration at a dose rate of 1 mg/kg body weight when compared with conventional therapy using a control drug with equally good in vitro activity, produced significantly better therapeutic results.

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来源期刊
Tierarztliche Praxis
Tierarztliche Praxis VETERINARY SCIENCES-
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审稿时长
6-12 weeks
期刊最新文献
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