急性肾衰竭患者体外肾替代治疗的临时血管通路。

Kidney international. Supplement Pub Date : 1998-05-01
B Canaud, H Leray-Moragues, M Leblanc, K Klouche, C Vela, J J Béraud
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引用次数: 0

摘要

在急性肾衰竭患者中,临时血管通路是进行体外肾替代治疗(RRT)的必要组成部分。急性情况下使用的RRT可分为两组:间歇(IRRT)和连续(CRRT)。治疗指征基于临床和技术考虑。连续模式主要用于重症监护病房的血液动力学受损的病人。CRRT最初是通过动静脉循环自发进行的,在血泵的循环辅助下,CRRT模式逐渐变成静脉静脉。由于间歇和连续RRT模式现在几乎完全由静脉-静脉模式执行,本文专门处理临时静脉导管。目前,双腔导管是RRT模式中最常见的血管通路。目前在紧急情况下使用的半刚性聚氨酯导管仅限于短期使用。血液相容、灵活的硅胶导管,对血管的伤害较小,似乎更适合中长期使用。隧道硅胶导管(DualCath型)满足短期和长期需求,并允许血液流速高达400毫升/分钟。颈内静脉,特别是右静脉,似乎可以保证导管的正常功能,同时降低狭窄并发症的风险。锁骨下通路应及时限制,并保留硅胶导管,以限制狭窄和/或血栓形成的风险。股骨通路在急诊和呼吸问题的情况下非常有用,但极大地损害了患者的活动能力,应限制时间,以防止血栓形成和/或感染。晚期和/或迟发性导管功能障碍提示血栓形成。在连续低流量RRT模式中,导管的性能标准不是一个限制因素,而在间歇RRT模式中则不是。最后,小心处理导管对防止感染并发症至关重要。
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Temporary vascular access for extracorporeal renal replacement therapies in acute renal failure patients.

Temporary vascular access is an essential component to perform any extracorporeal renal replacement therapy (RRT) in the acute renal failure patient. RRT used in the acute setting may be categorized in two groups: intermittent (IRRT) and continuous (CRRT). Therapeutic indications are based on clinical and technical considerations. Continuous modalities are mainly utilized in intensive care units for hemodynamically compromised patient. Initially performed spontaneously via an arteriovenous circuit, CRRT modalities have progressively become venovenous with the circulatory assistance of a blood pump. Since both intermittent and continuous RRT modalities are now performed almost exclusively by venovenous modalities, this article deals exclusively with temporary venous catheters. At present, double-lumen catheters represent the most common vascular access for RRT modalities. Semi-rigid polyurethane catheters currently used in case of emergency are limited to short term use. Hemocompatible, flexible silicone catheters, less aggressive for the vessels, seem better suited for the medium and long term run. The tunneled silicone catheters (DualCath type) meet the short and long term needs, and allow for blood flow rates up to 400 ml/min. The internal jugular vein, particularly the right one, seems to warrant the proper functioning of catheters while reducing the risk of stenotic complications. Subclavian access should be limited in time and reserved for silicone catheters in order to limit the risk of stenosis and/or thrombosis. Femoral access, very useful in cases of emergency and respiratory problems, greatly impairs the patient's mobility and should be limited by time to prevent thrombosis and/or infection. Late and/or delayed dysfunctioning of catheters are indicative of a thrombosis. Performance standards of catheters are less of a limiting factor in continuous low flow RRT modalities than in the intermittent ones. Finally, careful handling of the catheter essential to prevent infectious complications.

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Alport syndrome. New strategies to prevent cardiovascular risk in chronic kidney disease. Proceedings of the Sixth International Conference on Hypertension and the Kidney. February 2008. Madrid, Spain. Prevention of Renal Disease in the Emerging World: Toward Global Health Equity. Proceedings of the Bellagio Conference, March 16-18, 2004, Italy. The in vitro biocompatibility performance of a 25 mmol/L bicarbonate/10 mmol/L lactate-buffered peritoneal dialysis fluid. Proceedings of the Third International Conference on Hypertension and the Kidney, February 2002, Madrid, Spain.
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