[人群中最小红斑剂量和皮肤天然光防护的测定]。

K Ettler
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引用次数: 0

摘要

导论部分从物理和生物学的角度综述了紫外线对人体皮肤的影响,特别是光老化和光致癌作用。特别注意的是皮肤的光型,表征个体对紫外线的敏感性。最小红斑剂量(MED)用于建立这种敏感性。其他国家白人的平均药物耐受性也显示在这里。自然光保护的机制以及如何增加人工光保护的说明在这里进行了描述。调查我国人群皮肤类型的发病率,确定他们对UV-B和多色光的平均med是实际工作的目的。UV-B MED平均为23.4 mJ/cm2。进一步的工作集中在辐照后色素沉着反应的评估,特别是在季节前和季节后最小红斑剂量的比较。结果表明,夏季日光照射后MED平均增加一倍。我们认为,季节性天然光防护的两倍增加并不代表对大多数人的绝对保护,也不影响基于冬季med的媒体夏季预警系统。最后提出了一些改善捷克人民对紫外线辐射防护的建议。
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[Determination of the minimal erythema dosage and natural photoprotection of the skin in the population].

Effects of ultraviolet radiation (UV) on the human skin are summarized in the introductory part from physical and biological point of view, especially photoaging and photocarcinogenesis. Special attention has been paid to skin phototype which characterizes the individual susceptibility to UV. The minimal erythema dose (MED) serves for establishment of this susceptibility. The mean MEDs for white population in other countries are also shown here. Mechanisms of natural photoprotection in connection with instructions how to increase artificial photoprotection are described here. The investigation of skin type incidence in our population and determining their mean MEDs for UV-B and polychromatic light was the aim of practical work. The UV-B MED is in average 23.4 mJ/cm2. The further work has been concentrated on the assessment of pigmentation response after irradiation and especially on the comparison of the minimal erythema doses before season and after it. We found mean double increase of the MED after sunlight exposition during summer season. We suggested, that double increasing of seasonal natural photoprotection does not represent definitive protection for most people and does not impair summer warning system in media which is based on winter MEDs. Some recommendations for improvement of protection of Czech population against UV radiation are proposed in conclusion.

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