神经痛性神经病——复杂的发病机制和治疗。三叉神经痛——神经痛性肩肌萎缩症——疱疹后神经痛。

Fortschritte der Medizin Pub Date : 1999-05-10
H M Meinck
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引用次数: 0

摘要

广泛的表现和原因使得神经痛性神经病的诊断困难。然而,在大多数情况下,可以确定周围神经紊乱的临床和/或电生理体征。疼痛的病理机制是复杂的,尚未完全了解。它们并不局限于病变部位,而是包括整个周围神经元,甚至可能涉及中枢神经元。慢性疼痛的病理生物学相关性已被确定为涉及整个疼痛介导的神经通路。
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[Neuralgic neuropathies--complex pathogenesis and therapy. Trigeminal neuralgia--neuralgic shoulder amyotrophy--post-herpetic neuralgia].

A wide spectrum of manifestations and causes makes the diagnosis of neuralgic neuropathies difficult. In most cases, however, clinical and/or electrophysiological signs of a peripheral nerve disorder can be established. The pathomechanisms underlying pain are complex and not fully understood. They are not limited to the site of a lesion, but encompass the entire peripheral neurone, and may even involve the central neurones. Pathobiological correlates of chronic pain have been identified to involve the entire pain-mediating neuronal pathway.

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