[新生儿期猪骨髓红细胞代谢各环节及抗氧化系统的变化]。

H L Antoniak
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引用次数: 0

摘要

催化代谢(己糖激酶、磷酸果糖激酶、丙酮酸激酶、乳酸脱氢酶、2,3-二磷酸甘油变化酶、葡萄糖-6-磷酸脱氢酶、异柠檬酸脱氢酶和细胞色素氧化酶)和抗氧化系统(超氧化物歧化酶、研究了猪出生后10天及30日龄动物骨髓红细胞中谷胱甘肽过氧化物酶和谷胱甘肽还原酶的含量。结果表明,在新生儿发育时期,猪骨髓红核细胞发生了能量代谢的重组。它包括氧化过程的加强,在很大程度上是由激活2,3-二磷酸甘油酸变异酶的形成在自然红细胞。出生后早期观察到猪骨髓红细胞抗氧化系统的激活。
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[Changes in various links of metabolism and the antioxidant system in the bone marrow erythroid cells of the pig during the neonatal period].

The age dynamics of activities of enzymes which catalysis several stages of metabolism (hexokinase, phosphofructokinase, pyruvate kinase, lactate dehydrogenase, 2,3-diphosphoglycerate mutase, glucose-6-phosphate dehydrogenase, isocitrate dehydrogenase and cytochrome oxidase) and antioxidant system (superoxide dismutase, glutathione peroxidase and glutathione reductase) was studied in the bone marrow erythroid cells of pig during the 10-day period after birth as well as in the cells of 30 days old animals. It was established that in the neonatal period of development the reorganization of energy metabolism in pig bone marrow erythrokaryocytes took place. It consisted in the intensification of oxidative processes and in a great measure was directed on the activation of 2,3-diphosphoglycerate mutase formation in the nature red cells. During the early period after birth the activation of antioxidant system in erythroid cells of pig bone marrow was observed.

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