对直接压缩片剂的不同赋形剂的概述

Mira Jivraj , Luigi G. Martini , Carol M. Thomson
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引用次数: 479

摘要

简陋的片剂剂型仍然占给人所有剂型的80%以上。本综述将概述在直接压缩配方中用作填充剂的各种赋形剂,并特别强调这些赋形剂在其功能方面的期望。这篇概述(这绝不是详尽无遗的)将作为配方科学家的“备忘录”。
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An overview of the different excipients useful for the direct compression of tablets

The humble tablet dosage form still accounts for more than 80% of all dosage forms administered to man. This review will outline the various excipients that have been used as fillers in direct compression formulations, with particular emphasis on what is expected from such excipients in terms of their functionality. It is intended that this overview (which is by no means exhaustive) will serve as an ‘aide-memoire’ to the formulation scientist.

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