淀粉胶囊:口服给药的替代系统

Vinod D Vilivalam, Lisbeth Illum, Khurshid Iqbal
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引用次数: 77

摘要

淀粉胶囊通过注射成型工艺制造,已被证明是一种非常有用的口服给药化合物的替代递送系统。本文介绍了淀粉胶囊的制备和填充工艺,并对淀粉胶囊的物理特性进行了概述。此外,还描述了支持基于淀粉胶囊的新型递送技术开发的研究。特别强调的是一种技术,促进药物输送到人体胃肠道的特定部位。
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Starch capsules: an alternative system for oral drug delivery

Manufactured by the process of injection moulding, starch capsules have been shown to be a very useful alternative delivery system for orally administered compounds. This review describes the starch capsule manufacturing and filling processes and provides an overview of the capsules’ physical characteristics. In addition, investigations supporting the development of novel delivery technologies based on the starch capsules are described. Particular emphasis is given to a technology that facilitates drug delivery to specific sites in the human gastrointestinal tract.

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