[表面膜受体的药物激动剂和拮抗剂的共同特性]。

Voprosy meditsinskoi khimii Pub Date : 1999-11-01
A I Luĭk, V V Prokopenko, V Iu Tanchuk, V V Kholodovich, I V Semeniuta
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引用次数: 0

摘要

利用体外实验转录模型和电子拓扑计算方法,在阻断和激活细胞外受体的生理活性化合物(PAC)基团中发现了药理学和结构群落的元素。这一发现证实了将生物底物阻断剂和活化剂细分为PAC分层分类的必要性。
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[Common properties of pharmacological agonists and antagonists of surface membrane receptors].

Using experimental transcription model in vitro, and method of electron-topological calculations the elements of pharmacological and structural community have been found in the groups of physiologically active compounds (PAC), blocking and activating external cellular receptors. This finding confirms the necessity of subdivision special groups of bio-substrates blockators and activators for hierarchical classification, of PAC.

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